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. 2023 Feb 3;11(2):345. doi: 10.3390/vaccines11020345

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Protective immunity against separate infection with each of S. flexneri 1b, 2a, 3a, 6, and Y serotype was induced in guinea pigs by systemic immunization with PLVF. The control group of guinea pigs was injected with saline.