Table 2.

Univariate and Multivariate Cox regression analysis on all-cause mortality.

Characteristics	Univariate Analysis			Multivariate Analysis (Model 1)			Multivariate Analysis (Model 2)
	HR	95% CI	p	HR	95% CI	p	HR	95% CI	p
Log-transformed age (1 increase)	4.45	0.77–25.58	NS	2.42	0.39–15.09	NS	2.56	0.41–16.15	NS
Log-transformed creatinine (1 increase)	2.45	1.49–4.04	<0.01	2.67	1.46–4.89	<0.01	2.73	1.47–5.06	<0.01
Log-transformed BNP (1 increase)	1.75	1.13–2.72	0.01	1.35	0.91–2.00	NS	1.34	0.91–1.99	NS
CSR—yes	2.58	1.15–5.79	0.02	3.92	1.64–9.39	<0.01
CONUT (with malnutrition)	6.31	1.49–26.75	0.01	5.77	1.33–25.00	0.03
Non-CSR/without malnutrition	Reference						Reference
Non-CSR/with malnutrition	3.09	0.39–24.76	NS				2.10	0.25–17.10	NS
CSR/without malnutrition	0.88	0.06–14.03	NS				0.97	0.06–15.63	NS
CSR/with malnutrition	10.76	1.42–81.35	0.02				9.30	1.23–70.47	0.03

Model 1 includes age, creatinine, BNP, CSR and CONUT. Model 2 includes age, creatinine, BNP and the combined group of CSR and malnutrition. BNP, B-type natriuretic peptide; CSR, Cheyne-stokes respiration; CONUT, controlling nutritional status; NS, not significant.