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. 2023 Feb 1;16(2):225. doi: 10.3390/ph16020225

Figure 3.

Figure 3

Recordings of KATP channel inhibition in thallium-flux assays. Representative fluorescence intensity traces in the absence or presence of glibenclamide (Glib, 1 µM) measured at (A) Kir6.1/SUR2B that was activated using 1 µM P1075, (B) Kir6.2/SUR1 that was activated using 3 µM NN414, and (C) Kir6.2/SUR2A that was activated using 10 µM P1075. The measured fluorescence intensity units (FIU) were recorded as a function of time and for each of the individual cell lines vehicle control traces are depicted as well.