ACC |
Acetyl-CoA carboxylase |
ACLY |
ATP citrate synthase |
ACTH |
Adrenocorticotropic hormone |
AGE |
Advanced glycation end product |
AMPK |
AMP-activated kinase |
ApoE |
Apolipoprotein E |
ATF4 |
Activating transcription factor 4 |
ATG |
Autophagy target gene |
BAX |
Bcl2-associated X protein |
Bcl-2 |
B-cell/CLL lymphoma 2 |
BMAL-1 |
Brain and muscle arnt-like 1 |
CBP |
3′,5′-cyclic monophosphate-responsive element binding protein |
C/EBP |
CCAAT-enhancer-binding protein |
CHOP |
C/EBP homologous protein |
CREB |
cAMP-responsive element binding protein |
CRL |
Cullin RING ubiquitin ligase |
CSN |
COP9 signalosome |
DIM |
3′3-Diindolylmethane |
DNA-PKcs |
DNA-dependent protein kinase catalytic subunit |
DOCK4 |
Dedicator of cytokinesis 4 |
DUB |
Deubiquitinating enzyme |
ECM |
Extracellular matrix |
EDL |
Extensor digitorum longus |
EMT |
Epithelial-to-mesenchymal transition |
ER |
Endoplasmic reticulum |
ERAP1 |
Endoplasmic reticulum aminopeptidase 1 |
ERK |
Extracellular signal-regulated kinase |
FABP4 |
Fatty acid binding protein 4 |
FASN |
Fatty acid synthase |
FoxP3 |
Forkhead box P3 |
FSTL1 |
Follistatin-like protein 1 |
GATA1 |
GATA binding protein 1 |
GLUT |
Glucose transporter |
GM-CSF |
Granulocyte macrophage-colony stimulating factor |
G6PC |
Glucose-6-phosphatase catalytic subunit |
HAUSP |
Herpesvirus-associated ubiquitin-specific protease |
HCC |
Hepatocellular carcinoma |
HDL |
High-density lipoprotein |
HIF1α |
Hypoxia-inducible factor 1α |
HMGCR |
HMG-CoA reductase |
HOMA-IR |
Homeostasis model assessment-insulin resistance |
HOX1 |
Heme oxygenase-1 |
HSD1 |
11β-hydroxysteroid dehydrogenase 1 |
HUVEC |
Human umbilical vein endothelial cell |
IDOL |
Inducible degrader of the LDLR |
IFN |
Interferon |
IκB-α |
Nuclear factor of κ light polypeptide gene enhancer in B-cells inhibitor-α |
IL |
Interleukin |
IRS1 |
Insulin receptor substrate 1 |
JAK |
Janus kinase |
JAMM |
JAB1/MPN/Mov34 metalloproteases |
JNK |
c-Jun N-terminal kinase |
KO |
Knockout |
KLF4 |
Krüppel-like factor 4 |
LC3B |
Microtubule-associated protein light chain 3B-1 |
LDL |
Low-density lipoprotein |
LDLR |
LDL receptor |
LKB1 |
Liver kinase B1 |
LncRNA |
Long non-coding RNA |
LPS |
Lipopolysaccharide |
MAFLD |
Metabolic-dysfunction-associated fatty liver disease |
MAPK |
Mitogen-activated kinase |
MAT |
Methionine adenosyltransferase |
MCDD |
Methionine and choline-deficient diet |
MCPIP |
Monocyte chemotactic protein-induced protein |
MDA5 |
Melanoma differentiation-associated protein 5 |
Mdm2 |
Murine double minute 2 |
MINDY |
Motif interacting with ubiquitin-containing novel DUB |
miR-320 |
Micro RNA-320 |
MJD |
Machado-Joseph disease protein domain protease |
mTOR |
Mammalian target of rapamycin |
Myh |
Myosin heavy chain |
NADPH |
Nicotinamide adenine dinucleotide phosphate |
NAFL |
Non-alcoholic fatty liver |
NAFLD |
Non-alcoholic fatty liver disease |
NASH |
Non-alcoholic steatohepatitis |
NICD1 |
Noch1 intracellular domain 1 |
NLRC5 |
NOD-like receptor family cascade recruitment domain family domain containing 5 |
NQO1 |
NAD(P)H: quinone oxidoreductase 1 |
NF-κB |
Nuclear factor of κ light polypeptide gene enhancer in B-cells |
Nrf2 |
Nuclear factor erythroid 2-related factor 2 |
OTU |
Ovarian tumor domain-containing proteases |
PCK |
Phosphoenolpyruvate carboxykinase 1 |
PD |
Primaquine diphosphate |
PDGF-BB |
Platelet-derived growth factor-BB |
PDK1 |
3-Phosphoinositide-dependent protein kinase 1 |
PGC |
Peroxisome proliferator-activated receptor γ coactivator |
PI3K |
Phosphatidyl inositol 3 kinase |
PiT1 |
Phosphate inorganic transporter 1 |
PKA |
cAMP-dependent kinase |
POMC |
Proopiomelanocortin |
PPARγ |
Peroxisome proliferator-activated receptor γ |
PRDX3 |
Peroxiedoxin-3 |
PSMD |
26S Proteasome non-ATPase regulatory subunit |
RAC1 |
RAS-related C3 botulinus toxin substrate 1 |
RAGE |
Receptor for AGEs |
RIPK |
Receptor-interacting protein kinase 1 |
ROS |
Reactive oxygen species |
shRNA |
Short hairpin RNA |
Sirt |
Sirtuin |
SORT |
Sterol O-acetyltransferase |
SPAG5 |
Sperm-associated antigen 5 |
SPAG-AS1 |
SPAG-antisense1 |
SRA-1 |
Class A1 scavenger receptor |
SREBP1c |
Sterol regulatory element binding protein 1c |
STAT |
Signal transducer and activator of transcription |
STZ |
Streptozotocin |
TAK1 |
Transforming growth factor-β activated kinase 1 |
T1DM |
Type 1 Diabetes Mellitus |
T2DM |
Type 2 Diabetes Mellitus |
TEC |
Tubular epithelial cell |
TGF-β |
Transforming growth factor-β |
TNF-α |
Tumor necrosis factor-α |
TRAF6 |
Tumor necrosis factor receptor-associated factor 6 |
Treg |
Regulatory T-cell |
UBA |
Ubiquitin-associated domain |
UCH |
Ubiquitin C-terminal hydrolase |
UIM |
Ubiquitin-interacting motif |
UPS |
Ubiquitin–proteasome system |
USP |
Ubiquitin-specific protease |
VCAM1 |
Vascular cell adhesion molecule 1 |
VEGF |
Vascular endothelial cell growth factor |
VMH |
Ventromedial hypothalamus |
VLDL |
Very low-density lipoprotein |
WT-1 |
William tumor-1 |
ZNF638 |
Zinc finger protein 638 |
ZnF-UBP |
Zinc finger ubiquitin-specific protease domain |
ZUFSP |
Zinc finger and UFSP domain protein |