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. 2023 Feb 8;24(4):3430. doi: 10.3390/ijms24043430

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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The MTT assay results presenting the analyzed compounds and combinations activity: (A)—AmB, C1, and C1+AmB activity against C. albicans biofilms, (B)—AmB, NTBD, and NTBD+AmB activity against C. albicans biofilms, (C)—AmB, C1, and C1+AmB activity against C. parapsilosis biofilms, (D)—AmB, NTBD, and NTBD+AmB activity against C. parapsilosis biofilms, *—the statistically significant differences (p < 5%) in the metabolic activity of Candida biofilms treated with AmB, thiadiazole derivatives and their combinations compared with the control, #—the statistically significant differences (p < 5%) in the metabolic activity Candida biofilms treated with thiadiazole derivatives + AmB compared with biofilms subjected to AmB.