Table 1.

MeCP2-linked neurodevelopmental disorders and metabolic impairments.

Diseases	Metabolic Impairments	References
Rett Syndrome	Abnormal systemic and brain glucose utilization as well as insulin resistance Impaired systemic and brain cholesterol metabolism Abnormal mitochondrial function	[18,19,20,21,22,23,24,25]
Autism Spectrum Disorders	Altered brain glucose utilization and insulin resistance dyslipidemia	[26,27,28]
Fetal Alcohol Spectrum Disorders	Impaired glucose tolerance Increase plasma triglyceride level	[29]
Severe Neonatal Encephalopathy	Impaired mitochondrial oxidative phosphorylation	[30,31]