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EMPA-sEV improves cardiac function and reduces infarct size in MI. (a) Representative echocardiographic images of different groups at 23 and 36 days after MI (n = 3). (b, c) LVEF and LVFS were assessed in different groups after MI (n = 3). (d) Masson staining and infarct size quantitative analysis of heart sections in different groups (scale = 1000 μm, 200 μm) (n = 3). Data are expressed as mean ± SEM. ∗P < 0.05, ∗∗P < 0.01, ∗∗∗P < 0.001, and ∗∗∗∗P < 0.0001.
