ALS	amyotrophic lateral sclerosis
ALSFRS-R	amyotrophic lateral sclerosis functional rating scale revised
ApoE	apolipoprotein E
Asah1	acid ceramidase
BBB	blood-brain barrier
BDNF	brain-derived neurotrophic factor
C9ORF72	chromosome 9 open reading frame 72
CNS	central nervous system
CSF	cerebrospinal fluid
FUS	fused in sarcoma
FVT1	3-ketodihydrosphingosine reductase
GCS	glucosylceramide synthase
HEX	hexosaminidase
HDL	high-density lipoproteins
IL-6	Interleukin-6
iPS cells	induced pluripotent stem cell
LPO	lipid peroxidation
LDL	low-density lipoproteins
MCT1	monocarboxylate transporter 1
Nrf2	nuclear factor erythroid-derived 2-like 2
PUFAs	saturated fatty acids
SMA	spinal muscular atrophy
SMS	sphingomyelin synthase
SOD1	superoxide dismutase 1
SPT	serine palmitoyltransferase
SPTLC1	subunit 1 of the long chain serine palmitoyltransferase
TDP-43	TAR DNA binding protein
TFIID	transcription factor II D
TNF-α	tumor necrosis factor
UGCG	UDP-glucose ceramide glycosyltransferase
UGT8	galactosyltransferase
VCP	valosin containing protein