| (+) | positive-sense |
| (−) | negative-sense |
| APC | Antigen-presenting cell |
| BC | Baltimore Class |
| CDDI | Cortellis Drug Discovery Intelligence |
| CDKis | CDK inhibitors |
| CDKs | Cyclin-dependent kinases |
| GAK | Cyclin G associated kinase (GAK) |
| DAA | Direct acting antiviral |
| ds | double-stranded |
| FDA | Food and Drug Administration |
| FDR | False discovery rate |
| HAND | HIV-1-associated neurocognitive disorders |
| HTA | Host targeted antiviral |
| ICTV | International Committee on Taxonomy of Viruses |
| KEGG | Kyoto Encyclopedia of Genes and Genomes |
| MAPK | Mitogen-activated protein kinase |
| MLKL | Mixed lineage kinase-like protein |
| PKC | Protein kinase C |
| PKR | Protein kinase RNA-activated |
| PRR | Pattern recognition receptors |
| R&D | Research and development |
| RdRp | RNA-dependent RNA polymerase |
| RIG-1 | Retinoic acid-inducible gene 1 |
| RIPK | Receptor interacting protein kinase |
| RLR | Retinoic acid-inducible gene 1(RIG-I)-like receptor |
| RT | reverse transcribing |
| RTK | Receptor tyrosine kinase |
| RTz | Reverse transcriptase enzyme |
| ss | single-stranded |
| TLR | Toll-like receptor |
| UAD | Under active development |