Table 1.
Material | Virus/Disease | Recognition Element | Dynamic Range | LOD | Real Sample | Reference |
---|---|---|---|---|---|---|
AuNPs | Dengue | PNA | 0–12 µM | 0.12 µM | - | [57] |
AgNPs | MERS-CoV, HPV | PNA | 20–1000 nM (MERS-CoV), 20–2500 nM (HPV) | 1.53 nM (MERS-CoV), | - | [59] |
AuNPs | HPV genotype 16 and 18 |
DNA probe | 105 to 100 copies | 102 (HPV 16) and 101 (HPV 18) | clinical cervical tissue specimens | [62] |
AuNRs | HBV | DNA | 0.045 to 6.0 nM | 15 pM | Human blood | [68] |
AuNPs | HBV, HCV | DNA | - | HBV: 3.6 × 104 fM; HCV: 3.6 × 105 fM | Serum | [69] |
AuNPs | Influenza | aptamer | - | 2 × 106 copies/mL | - | [70] |
Zika virus | Nucleic acids | - | 5 PFU/mL | Saliva | [71] | |
AuNPs, AgNPs | Herpesvirus | DNA | 10 pM–1 µM | 1 nM | - | [72] |
Influenza A and B virus | aptamer | 0.1 pg/mL– 1 mg/mL |
0.30 pg/mL, 0.16 pg/mL | Patient samples | [73] | |
Copper nanoclusters | HBV | DNA | 12 × 109 to 12 × 1013 molecules | 12 × 109 molecules | Human serum | [74] |
AuNPs | HCV | oligonucleotides | 7.50 × 102 to 2.00 × 106 IU/mL | 100 IU/mL (0.4 IU/µL) | Human blood | [75] |
AuNPs | Cyprinid herpesvirus-3 (CyHV-3) | DNA | 100 ng/µL to 0.1 fg/µL | 10 fg CyHV-3-AuNP DNA (30 virions) | Infected fish tissues | [76] |