Table 3.
2007–2008 | 2009–2010 | 2017–2018 | p-Value | |
---|---|---|---|---|
Dietary intake of flavonoids (mg/day) | ||||
Daidzein | 0.62 ± 0.08 | 0.79 ± 0.05 | 0.93 ± 0.13 | 0.09 |
Genistein | 0.84 ± 0.10 | 1.12 ± 0.07 | 1.36 ± 0.19 | 0.02 |
Glycitein | 0.11 ± 0.01 | 0.16 ± 0.01 | 0.21 ± 0.03 | 0.01 |
Cyanidin | 2.22 ± 0.19 | 2.99 ± 0.25 | 2.82 ± 0.42 | 0.04 |
Petunidin | 0.77 ± 0.10 | 1.38 ± 0.18 | 1.40 ± 0.17 | 0.001 |
Delphinidin | 1.04 ± 0.13 | 2.10 ± 0.29 | 1.96 ± 0.24 | <0.001 |
Malvidin | 4.05 ± 0.46 | 5.23 ± 0.47 | 5.36 ± 0.56 | 0.11 |
Pelargonidin | 1.44 ± 0.21 | 1.88 ± 0.25 | 1.60 ± 0.16 | 0.36 |
Peonidin | 1.23 ± 0.12 | 2.11 ± 0.30 | 2.85 ± 0.32 | <0.0001 |
Catechin | 7.71 ± 0.32 | 8.18 ± 0.24 | 7.58 ± 0.33 | 0.26 |
Epigallocatechin | 17.41 ± 1.11 | 15.93 ± 1.30 | 16.76 ± 1.57 | 0.66 |
Epicatechin | 10.24 ± 0.41 | 10.13 ± 0.37 | 9.97 ± 0.41 | 0.9 |
Epicatechin 3-gallate | 11.50 ± 0.74 | 10.44 ± 0.88 | 10.41 ± 0.98 | 0.53 |
Epigallocatechin 3-gallate | 30.12 ± 1.90 | 27.50 ± 2.25 | 28.75 ± 3.60 | 0.64 |
Theaflavin | 1.77 ± 0.12 | 1.59 ± 0.14 | 1.41 ± 0.15 | 0.22 |
Thearubigins | 101.89 ± 6.79 | 91.63 ± 8.00 | 79.87 ± 7.67 | 0.14 |
Eriodictyol | 0.19 ± 0.01 | 0.20 ± 0.01 | 0.14 ± 0.01 | 0.004 |
Hesperetin | 9.55 ± 0.61 | 10.05 ± 0.35 | 7.24 ± 0.35 | <0.0001 |
Naringenin | 3.52 ± 0.29 | 3.40 ± 0.20 | 3.26 ± 0.30 | 0.82 |
Apigenin | 0.23 ± 0.03 | 0.31 ± 0.07 | 0.17 ± 0.01 | 0.03 |
Luteolin | 0.64 ± 0.04 | 0.74 ± 0.03 | 0.74 ± 0.04 | 0.11 |
Isorhamnetin | 0.80 ± 0.04 | 0.90 ± 0.03 | 0.87 ± 0.03 | 0.08 |
Kaempferol | 4.55 ± 0.19 | 4.64 ± 0.16 | 4.74 ± 0.12 | 0.7 |
Myricetin | 1.51 ± 0.07 | 1.46 ± 0.08 | 1.64 ± 0.07 | 0.23 |
Quercetin | 11.70 ± 0.41 | 11.91 ± 0.30 | 10.58 ± 0.24 | 0.004 |
Theaflavin-3,3′-digallate | 1.96 ± 0.14 | 1.76 ± 0.16 | 1.55 ± 0.17 | 0.2 |
Theaflavin-3′-gallate | 1.66 ± 0.12 | 1.49 ± 0.13 | 1.32 ± 0.14 | 0.23 |
Theaflavin-3-gallate | 1.42 ± 0.10 | 1.27 ± 0.12 | 1.10 ± 0.12 | 0.17 |
Gallocatechin | 1.87 ± 0.12 | 1.71 ± 0.14 | 1.55 ± 0.12 | 0.23 |
Subtotal Catechins | 78.85 ± 4.38 | 73.90 ± 5.11 | 75.03 ± 6.76 | 0.72 |
Total Isoflavones | 1.58 ± 0.19 | 2.06 ± 0.13 | 2.50 ± 0.34 | 0.04 |
Total Anthocyanidins | 10.74 ± 0.91 | 15.68 ± 1.09 | 15.99 ± 1.48 | <0.001 |
Total Flavan-3-ols | 187.55 ± 11.60 | 171.63 ± 13.66 | 160.28 ± 11.43 | 0.27 |
Total Flavanones | 13.26 ± 0.87 | 13.65 ± 0.52 | 10.64 ± 0.58 | 0.001 |
Total Flavones | 0.87 ± 0.05 | 1.05 ± 0.08 | 0.91 ± 0.04 | 0.18 |
Total Flavonols | 18.56 ± 0.68 | 18.92 ± 0.52 | 17.82 ± 0.40 | 0.26 |
Total Sum of all 29 flavonoids | 232.55 ± 12.43 | 222.98 ± 14.09 | 208.13 ± 11.66 | 0.39 |
Baseline sociodemographic, lifestyle, and health-related variables | ||||
Age, years | 46.85 ± 0.47 | 46.96 ± 0.51 | 47.29 ± 0.55 | 0.82 |
Gender, % | 0.41 | |||
Female | 53.69% (51.99%, 55.40%) | 52.22% (51.03%, 53.40%) | 52.15% (49.83%, 54.47%) | |
Male | 46.31% (44.60%, 48.01%) | 47.78% (46.60%, 48.97%) | 47.85% (45.53%, 50.17%) | |
Ethnicity, % | 0.16 | |||
Black | 11.15% (7.55%, 14.75%) | 11.49% (9.76%, 13.23%) | 11.61% (8.35%, 14.87%) | |
Mexican | 8.39% (5.63%, 11.16%) | 8.32% (4.51%, 12.13%) | 9.12% (5.80%, 12.44%) | |
Other | 9.91% (6.71%, 13.10%) | 11.56% (8.05%, 15.08%) | 17.06% (14.12%, 19.99%) | |
White | 70.55% (64.29%, 76.80%) | 68.62% (62.27%, 74.97%) | 62.22% (56.62%, 67.82%) | |
Education, % | 0.002 | |||
<9 years | 6.29% (4.87%, 7.71%) | 5.84% (4.53%, 7.15%) | 3.03% (2.14%, 3.92%) | |
9–12 years | 38.37% (34.35%, 42.38%) | 34.87% (32.08%, 37.67%) | 33.65% (30.25%, 37.04%) | |
>12 years | 55.34% (50.57%, 60.11%) | 59.29% (56.52%, 62.05%) | 63.32% (59.82%, 66.83%) | |
Marital status, % | 0.81 | |||
Without partner | 37.71% (33.75%, 41.68%) | 36.42% (34.30%, 38.54%) | 37.20% (34.42%, 39.98%) | |
With partner | 62.29% (58.32%, 66.25%) | 63.58% (61.46%, 65.70%) | 62.80% (60.02%, 65.58%) | |
PIR | 3.01 ± 0.09 | 2.96 ± 0.05 | 3.06 ± 0.06 | 0.47 |
BMI (kg/m2) | 28.74 ± 0.20 | 28.83 ± 0.13 | 29.77 ± 0.28 | 0.01 |
Daily energy intake (kcal) | 4120.26 ± 52.88 | 4207.67 ± 44.41 | 4140.31 ± 43.02 | 0.36 |
Total Score of HEI | 53.09 ± 0.65 | 54.30 ± 0.36 | 52.52 ± 0.71 | 0.04 |
DII | 1.65 ± 0.10 | 1.33 ± 0.04 | 1.45 ± 0.09 | 0.004 |
Total time of PA (mins/week) | 1274.92 ± 50.84 | 1102.61 ± 33.04 | 1463.02 ± 60.66 | <0.0001 |
Total MET of PA (/week) | 5094.71 ± 230.20 | 4243.83 ± 171.63 | 5870.06 ± 274.40 | <0.0001 |
Smoking status, % | 0.01 | |||
Never | 53.62% (50.24%, 57.00%) | 55.61% (51.57%, 59.66%) | 59.99% (56.97%, 63.01%) | |
Former | 24.11% (22.33%, 25.89%) | 25.11% (22.18%, 28.04%) | 24.13% (22.21%, 26.05%) | |
Now | 22.27% (19.75%, 24.79%) | 19.27% (17.31%, 21.24%) | 15.88% (13.51%, 18.25%) | |
Alcohol usage, % | <0.0001 | |||
Never | 11.56% (9.94%, 13.17%) | 10.87% (9.09%, 12.65%) | 9.62% (8.28%, 10.96%) | |
Former | 17.53% (14.56, 20.50) | 15.21% (13.27%, 17.15%) | 0.65% (0.33%, 0.98%) | |
Mild | 34.23% (30.60, 37.85) | 35.69% (32.90%, 38.47%) | 44.89% (41.47%, 48.31%) | |
Moderate | 15.60% (13.66, 17.54) | 16.65% (14.58%, 18.72%) | 21.97% (20.55%, 23.39%) | |
Heavy | 21.09% (19.46, 22.71) | 21.59% (19.12%, 24.05%) | 22.87% (20.11%, 25.63%) | |
Disease history at interview | ||||
DM, % | 0.45 | |||
No | 78.14% (75.37%, 80.90%) | 80.15% (78.17%, 82.13%) | 78.61% (76.44%, 80.79%) | |
Yes | 21.86% (19.10%, 24.63%) | 19.85% (17.87%, 21.83%) | 21.39% (19.21%, 23.56%) | |
Hyperlipidemia, % | 0.002 | |||
No | 28.37% (25.98%, 30.76%) | 29.88% (28.12%, 31.64%) | 35.17% (31.50%, 38.83%) | |
Yes | 71.63% (69.24%, 74.02%) | 70.12% (68.36%, 71.88%) | 64.83% (61.17%, 68.50%) | |
CVD, % | 0.96 | |||
No | 91.06% (90.00%, 92.12%) | 91.06% (89.71%, 92.41%) | 90.84% (89.16%, 92.53%) | |
Yes | 8.94% (7.88%, 10.00%) | 8.94% (7.59%, 10.29%) | 9.16% (7.47%, 10.84%) | |
Respiratory system disease, % | <0.0001 | |||
ACO | 2.58% (2.05%, 3.11%) | 2.11% (1.57%, 2.65%) | 1.87% (1.07%, 2.66%) | |
Asthma | 11.83% (9.90%, 13.75%) | 10.14% (9.25%, 11.04%) | 12.78% (11.05%, 14.51%) | |
COPD | 4.39% (3.46%, 5.33%) | 3.81% (2.65%, 4.98%) | 1.19% (0.80%, 1.58%) | |
No | 81.20% (78.58%, 83.82%) | 83.94% (82.45%, 85.42%) | 84.16% (81.87%, 86.44%) | |
Stroke, % | 0.49 | |||
No | 96.30% (95.59%, 97.00%) | 96.83% (96.33%, 97.34%) | 96.70% (95.99%, 97.40%) | |
Yes | 3.70% (3.00%, 4.41%) | 3.17% (2.66%, 3.67%) | 3.30% (2.60%, 4.01%) | |
Cancer, % | 0.46 | |||
No | 90.69% (89.63%, 91.75%) | 90.06% (88.86%, 91.26%) | 89.70% (88.56%, 90.83%) | |
Yes | 9.31% (8.25%, 10.37%) | 9.94% (8.74%, 11.14%) | 10.30% (9.17%, 11.44%) | |
Hypertension, % | 0.18 | |||
No | 63.63% (61.50%, 65.76%) | 64.67% (61.79%, 67.55%) | 61.19% (58.00%, 64.38%) | |
Yes | 36.37% (34.24%, 38.50%) | 35.33% (32.45%, 38.21%) | 38.81% (35.62%, 42.00%) |
Continuous variables are presented as mean ± standard deviation and categorical variables are presented as percentage (95% CIs).