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. 2023 Jan 18;15(2):274. doi: 10.3390/v15020274

Figure 3.

Figure 3

Crystal structures of gammaretrovirus receptor binding domains. Crystal structures of the receptor binding domain (RBD) of Friend MLV (PDB 1A0L), FeLV B (PDB 1LCS) and ENVp(b)1 (PDB 6W5Y). Defined variable regions A, B and C (VRA, VRB, VRC) are shown in blue for MLV and FeLV B. Approximate locations are indicated for EnvP(b)1 based on structurally similar locations (McCarthy et al., 2020). Variable regions are believed to provide receptor specificity among RBDs that recognize different receptors.