Table 2.

Equivalence of the hybridization LC-MS/MS assay for the quantification of siRNA-01 and AS1.

	siRNA-01 Low QC 6.00 ng/mL	AS1 Low QC 6.00 ng/mL	siRNA-01 + AS1 Low QC 3.00 + 3.00 ng/mL	siRNA-01 High QC 750 ng/mL	AS1 High QC 750 ng/mL	siRNA-01 + AS1 High QC 375 + 375 ng/mL
	6.46	6.27	5.80	696.41	752.41	733.57
	6.55	5.99	5.99	677.39	813.93	705.49
	6.92	6.50	5.10	782.65	761.66	680.36
	5.62	5.53	5.41	799.26	759.01	822.64
Mean	6.39	6.07	5.58	738.93	771.75	735.52
S.D.	0.55	0.42	0.40	60.95	28.39	62.02
n	4	4	4	4	4	4
% C.V.	8.6	6.9	7.2	8.2	3.7	8.4
% Nominal	106.5	101.2	92.9	98.5	102.9	98.1