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. 2023 Feb 7;11(2):155. doi: 10.3390/toxics11020155

Figure 3.

Figure 3

Changes in total glutathione level of pod-type ENDS aerosol exposed SAEC after 24 h and 7 days. The total glutathione level was significantly decreased by 43.25% (**, p < 0.01) in 101–150 puffs after the 24 h exposure to JUUL® Virginia tobacco 5% ENDS aerosol compared to the negative control (A). Even though there was no significance noted, the total GSH level was decreased by 31.44% also in 1–50 puffs at 24 h (A). After the 7 days of exposure, the total GSH level has significantly decreased by 44.39% (**, p < 0.01) and 40.50% (*, p < 0.05) in 1–50 puffs and 101–150 puffs, respectively, compared to the negative control (B). The Blank control, which contained vehicle solution for dilution, showed no difference compared to the negative control (B).