Table 2.
Histopathological scoring of different parameters of trachea and lung at experimental infection with LT_2 and LT_56 H9N2 viruses in Sonali and broiler chickens.
| Infected Groups | Sonali Chickens | Broiler Chickens | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Lesions/Dpi | 1 | 3 | 5 | 7 | 10 | 15 | 1 | 3 | 5 | 7 | 10 |
| Trachea | |||||||||||
| Proliferation of goblet cells | + | + | + | + | + | + | +/− | + | − | ++ | ++ |
| Loss of epithelial layer | + | + | +++ | +++ | +++ | +++ | − | + | +++ | − | − |
| Loss of cilia | + | + | +++ | +++ | +++ | +++ | − | + | +++ | − | − |
| Inflammation | +/− | + | ++ | +++ | +++ | +++ | − | + | +++ | − | − |
| Congestion and | − | − | − | − | − | − | + | − | − | − | − |
| Hemorrhages | − | − | − | − | − | − | − | − | − | − | − |
| Lung | |||||||||||
| Congestion | + | ++ | ++ | +++ | + | +/− | ++ | ++ | +++ | + | + |
| Hemorrhage | + | + | ++ | +++ | + | +/− | ++ | + | +++ | + | +/− |
| Presence of inflammatory cells | +/− | +/− | + | + | + | +/− | +/− | +/− | ++ | + | + |
| Collapsing of alveoli | + | + | + | ++ | + | +/− | + | ++ | ++ | − | − |
| Rupture of alveoli | − | − | + | ++ | + | +/− | + | ++ | ++ | − | − |
| Loss of Pneumocyte−I | +++ | +++ | +++ | +++ | + | + | + | + | + | − | − |
| Increased proliferation of pneumocyte−I | − | − | − | − | + | + | − | − | − | − | − |
| Proliferation of pneumocyte−II | + | ++ | +++ | + | + | + | + | + | + | − | − |
| Intestine | |||||||||||
| Shortening of villi | − | ++ | − | − | − | − | − | + | − | − | − |
| Desquamation of villus epithelium | − | − | +++ | − | − | − | − | − | ++ | − | − |
| Infiltration of inflammatory cells | − | − | ++ | − | − | − | − | − | + | − | − |
| Glandular proliferation of crypt epithelium | − | − | ++ | − | − | − | − | − | + | − | − |