Table 3.
Variables | Group | Day 14 | Day 28 | Day 42 | |||
---|---|---|---|---|---|---|---|
Mean | SEM | Mean | SEM | Mean | SEM | ||
AST (IU/L) | C | 56.20 | 2.37 | 135.00 | 18.76 | 13.83 | 0.95 |
MO | 69.80 | 13.00 | 110.80 | 13.75 | 16.13 | 1.08 | |
MSC | 58.40 | 7.80 | 131.40 | 30.00 | 13.63 | 1.10 | |
MS | 64.20 | 5.10 | 137.60 | 30.56 | 12.14 | 1.67 | |
Significance | NS | NS | NS | ||||
ALT (IU/L) | C | 50.00 | 1.52 | 38.20 | 3.38 | 26.50 | 1.82 |
MO | 52.80 | 7.44 | 34.40 | 3.18 | 27.25 | 2.19 | |
MSC | 54.20 | 2.73 | 42.20 | 3.18 | 28.88 | 2.22 | |
MS | 53.20 | 2.63 | 39.40 | 1.81 | 25.43 | 1.04 | |
Significance | NS | NS | NS | ||||
Glucose (mmol/L) | C | 9.18 | 0.35 | 9.02 | 0.16 | 8.20 | 0.45 |
MO | 8.98 | 0.53 | 8.72 | 0.22 | 7.89 | 0.31 | |
MSC | 8.96 | 0.38 | 8.72 | 0.39 | 7.48 | 0.21 | |
MS | 8.72 | 0.56 | 8.96 | 0.29 | 7.84 | 0.15 | |
Significance | NS | NS | NS | ||||
Cholesterol (mmol/L) | C | 4.48 | 0.13 | 5.40 | 0.37 | 4.38 | 0.25 |
MO | 4.50 | 0.21 | 5.36 | 0.34 | 3.84 | 0.11 | |
MSC | 4.54 | 0.10 | 5.24 | 0.26 | 4.23 | 0.22 | |
MS | 4.36 | 0.27 | 5.18 | 0.51 | 5.14 | 0.66 | |
Significance | NS | NS | NS | ||||
Triglycerides (mmol/L) | C | 1.73 | 0.27 | 0.99 | 0.13 | 1.66 | 0.28 |
MO | 1.46 | 0.27 | 0.89 | 0.07 | 1.75 | 0.39 | |
MSC | 1.89 1.20 |
0.28 | 1.08 | 0.14 | 1.18 | 0.14 | |
MS | 1.20 | 0.22 | 1.06 | 0.11 | 1.01 | 0.16 | |
Significance | NS | NS | NS | ||||
Creatinine (µmol/L) | C | 21.00 | 0.71 | 19.00 b | 0.45 | 18.50 b | 0.81 |
MO | 22.40 | 0.68 | 23.20 a | 1.39 | 23.00 a | 1.00 | |
MSC | 21.40 | 0.68 | 21.20 ab | 0.07 | 21.88 ab | 1.03 | |
MS | 21.80 | 1.62 | 20.80 ab | 0.73 | 21.57 ab | 1.17 | |
Significance | NS | p < 0.05 | p < 0.05 | ||||
Uric acid (µmol/L) | C | 244.40 | 51.52 | 114.40 | 11.89 | 196.67 | 30.60 |
MO | 292.40 | 74.67 | 142.20 | 17.25 | 174.13 | 21.70 | |
MSC | 206.20 | 17.35 | 181.00 | 15.54 | 150.13 | 9.99 | |
MS | 260.40 | 18.87 | 154.00 | 16.60 | 143.00 | 7.84 | |
Significance | NS | NS | NS |
C: control, MO: milk thistle oil, MSC: milk thistle seed cake, MS: milk thistle seed; NS: non-significant (p > 0.05). ab Means in the same column with different superscripts are significantly different (p < 0.05).