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. 2023 Jan 24;21(2):80. doi: 10.3390/md21020080

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Effects of diHEP-DPA and 5-FU on EMT via the STAT3 signaling pathway. (A) The level of E-cadherin, N-cadherin, and vimentin were detected by western blotting. The relative expression of (B) E-cadherin (C) N-cadherin, and (D) vimentin were calculated by ImageJ. (E) The level of STAT3 and pSTAT3 were detected by western blotting in isolated tumors and (F) were calculated by ImageJ. Data are expressed as mean ± SD; n = 3 per group. * p < 0.05 compared with the control group; ^# p < 0.05 compared with the 5-FU group.