Figure 2.

Putative involvement of myocytes in cutaneous leishmaniasis shown in sectioned ear pinna of a female BALB/c mouse infected with Leishmania major. Histological sections stained with green Masson’s trichrome. (A) Leishmania lesion in the ear pinna. (B) Detailed view showing infected macrophages (some of which are encircled) and muscle cells with putative amastigotes (arrowhead and the inset). Asterisk—lesion with massive cell infiltration, arrowhead—putative amastigotes, c—cartilage, e—epidermis, f—hair follicle, m—muscle, white circles—infected macrophages. The involvement of myocytes in cutaneous leishmaniosis requires further confirmation using more specific detection methods.