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. 2023 Feb 10;14(2):97. doi: 10.3390/jfb14020097

Table 2.

An overview of performance of CRISPR detection based on electrochemical signal sensing.

Method Target Test Time Sensitivity Reference
E-CRISPR Viral nucleic acids (HPV-16 and PB-19) 30 min 50 pM [39]
CRISPR/Cas12a-Mediated Electrochemical Nucleic Acid Sensing DNA 60 min 30 pM [40]
E-DNA Sensor DNA 60 min 10 fM [41]
CRISPR/Cas13a-Powered Electrochemical Microfluidic Biosensor microRNA 4 h 10 pM [42]
Label-free Impedance Biosensing bacterial DNA (E. coli and S. aureus) 1.5 h 3 nM [43]
Electrochemical Strategy for Low-Cost Viral Detection Viral nucleic acids (HIV and HPV) 3 h 104 copies [44]
RAA-based E-CRISPR bacterial DNA (L. monocytogenes) 1 h 26 CFU mL−1 [45]