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. 2023 Jan 18;15(2):319. doi: 10.3390/pharmaceutics15020319

Table 1.

GNPs modified with FDG-related molecules for biomedical applications.

Author GNPs Surface Agent Target Biomedical
Application
Roa et al. (2012) [72] 6-fluoro-6-deoxy-D-glucose Breast adenocarcinoma Radiosensitizer
Suvarna et al. (2017) [70] 2-deoxy-D-glucose cancer cell lines such as HepG2, HeLa and HCT 116 Theragnostic
Hu et al. (2015) [47] Glucose-coating Breast adenocarcinoma Radiosensitizer
Jiang et al. (2014) [69] PEGylation + 2-deoxy-D-glucose Brain glioma Drug-delivery
Unak et al. (2012) [71] 18F-2-fluoro-2-deoxy-D-glucose + Ab anti-metadherin (MTDH) Breast adenocarcinoma Theragnostic
Feng et al. (2014) [74] PEGylation + glucose-coating BALB/c nude mice CT imaging
contrast agent
Hu et al. (2015) [47] Glucose-coating Leukemic stem cell line THP-1 and breast cell line MCF-7 Radiosensitizer