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(A) Study protocol including vaccination, challenge infection and blood sampling; (B) The average percentage of blocking (%PB) and 95% confidence interval in vaccinated (solid circles) and control dogs (open squares) at the selected sampling points as determined by ELISA. The blood sample B10 was collected 11–91 days post challenge infection, depending on the day of euthanasia; (C) Survival probabilities of the two treatment groups.
