Table 2.
Vitamin C status relative to intake stratified by age.
| Reference | Population (Location) | n | Age (Years) | Vitamin C Dose (mg) and Time | Baseline Vitamin C (µmol/L) |
Post-Suppl. Vitamin C (µmol/L) |
p Value a |
|---|---|---|---|---|---|---|---|
| Blanchard 1990 [35] | 30 healthy young and older men (USA) | 15 | 25 ± 3 | 500 (4–5 h) | NR | 53 ± 24 | |
| 15 | 69 ± 3 | 500 (4–5 h) | NR | 45 ± 16 | NS | ||
| Blanchard 1990 [36] | 28 healthy young and older women (USA) | 14 | 26 ± 3 | 500 (4–5 h) | NR | 56 ± 27 | |
| 14 | 68 ± 3 | 500 (4–5 h) | NR | 57 ± 24 | NS | ||
| Blanchard 1989 [37] | 16 healthy young and older women (USA) | 8 | 20–29 | 500 (3 wk) | 78 ± 24 | 93 ± 23 | |
| 8 | 65–71 | 500 (3 wk) | 93 ± 40 | 104 ± 15 | NS | ||
| Murata 1995 [38] | 40 long-term hospitalised older people and healthy young adults (Japan) | 20 | 19–40 | 250 (28 d) | 29 ± 9 | 59 ± 10 | |
| 20 | 70–90 | 250 (28 d) | 15 ± 6 | 47 ± 8 | <0.01 | ||
| Murata 1993 [39] | 39 long-term hospitalised older people and healthy young adults (Japan) | 20 | 19–35 | 250 (24 h) | 31 ± 9 | 34 ± 9 | |
| 19 | 66–96 | 250 (24 h) | 17 ± 8 | 19 ± 7 | <0.01 |
Data represent mean and SD. a—p-value is for young vs. old groups post-supplementation. NR—not reported; NS—not significant.