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. 2023 Feb 3;11(2):396. doi: 10.3390/microorganisms11020396

Table 2.

Uni- and multi-variate analysis of association between interventions and sepsis-related mortality in late-onset sepsis among preterm very low birth weight infants.

Univariable Models Multivariable Model
OR (95% CI) p aOR (95% CI) p
Time to first antibiotics 0.85 (0.7–1.02) 0.087 0.90 (0.71–1.15) 0.408
Time to volume administration 0.92 (0.83–1.02) 0.129 0.89 (0.76–1.04) 0.130
Appropriate empirical antimicrobials Reference Reference
Inappropriate empirical antimicrobials 4.11 (1.1–15.36) 0.036 10.25 (1.37–76.75) 0.023
Undetermined appropriateness of empirical antimicrobials 6.09 (1.33–27.83) 0.020 4.12 (0.42–40.68) 0.226
Gram-positive pathogen Reference Reference
Gram-negative pathogen 3.89 (1.02–14.82) 0.047 9.85 (1.55–83.97) 0.036