Table 1.
Multivariate regression model of the association between each characteristic and cognitive deficit at A1.
| Tumour Volume (cm3) | Age at Surgery (Years) | IDH Status (Mutant) | MIB Index (%) | MGMT Methylation Status (Y/N) | Steroids Pre-operatively (Y/N) | AEDS1 (Y/N) | COVID Era (Y/N) | Age Left Education (Years) | ||
|---|---|---|---|---|---|---|---|---|---|---|
| Overall | 75.6 (22.4–108.9) | 58 (54–66) | 6% | 28.0 (19.5–33.0) | 40% | 90% | 31% | 27% | 18 (16–21) | |
| Deficit | 74.3 (5.6–268.1) | 58.3 (25–78) | 0 (0–1) | 28.6 (5–65) | 0.4 (0–1) | 0.9 (0–1) | 0.3 (0–1) | 0.1 (0–1) | 17.8 (14–23) | |
| Perception | No Deficit | 89.4 (14.1–164.6) | 56 (28–69) | 0.2 (0–1) | 20.9 (15–28) | 0.2 (0–1) | 0.8 (0–1) | 0 (0–0) | 0 (0–0) | 19.8 (16–26) |
| p.val | 0.70 | 0.83 | 0.23 | 0.05 | 0.64 | 0.36 | 0.29 | 1.00 | 0.49 | |
| Deficit | 80.2 (6.4–268.1) | 59.2 (25–78) | 0 (0–1) | 27.5 (5–65) | 0.4 (0–1) | 0.9 (0–1) | 0.3 (0–1) | 0 (0–1) | 17.8 (14–23) | |
| Memory | No Deficit | 51.6 (5.6–164.6) | 52.1 (28–61) | 0.1 (0–1) | 30.2 (18–50) | 0.5 (0–1) | 0.9 (0–1) | 0.1 (0–1) | 0.2 (0–1) | 19.2 (16–26) |
| p.val | 0.20 | 0.12 | 0.42 | 0.55 | 0.70 | 1.00 | 0.40 | 0.12 | 0.30 | |
| Deficit | 67.3 (6.4–137.3) | 58.4 (33–78) | 0.1 (0–1) | 23.7 (5–38) | 0.3 (0–1) | 0.9 (0–1) | 0.3 (0–1) | 0.1 (0–1) | 18.9 (15–23) | |
| Language | No Deficit | 78 (5.6–268.1) | 58 (25–74) | 0.1 (0–1) | 29.2 (9.2–65) | 0.4 (0–1) | 0.9 (0–1) | 0.3 (0–1) | 0.1 (0–1) | 17.7 (14–26) |
| p.val | 0.52 | 0.93 | 0.54 | 0.12 | 0.48 | 1.00 | 1.00 | 1.00 | 0.30 | |
| Deficit | 66.2 (6.4–248.5) | 62.7 (49–78) | 0 (0–0) | 21.2 (10–35) | 0.3 (0–1) | 1 (1–1) | 0.5 (0–1) | 0.2 (0–1) | 17 (15–19) | |
| Praxis | No Deficit | 76.9 (5.6–268.1) | 57.4 (25–74) | 0.1 (0–1) | 28.9 (5–65) | 0.4 (0–1) | 0.9 (0–1) | 0.3 (0–1) | 0.1 (0–1) | 18.1 (14–26) |
| p.val | 0.79 | 0.30 | 1.00 | 0.15 | 1.00 | 1.00 | 0.37 | 0.42 | 0.15 | |
| Deficit | 65.4 (6.4–137.3) | 60.3 (33–78) | 0.1 (0–1) | 26.2 (10–38) | 0.4 (0–1) | 1 (1–1) | 0.2 (0–1) | 0.1 (0–1) | 17.2 (15–23) | |
| Number | No Deficit | 77.8 (5.6–268.1) | 57.6 (25–74) | 0 (0–1) | 28.4 (5–65) | 0.4 (0–1) | 0.9 (0–1) | 0.3 (0–1) | 0.1 (0–1) | 18.2 (14–26) |
| p.val | 0.50 | 0.55 | 0.46 | 0.59 | 1.00 | 0.57 | 1.00 | 0.57 | 0.35 | |
| Deficit | 70.5 (5.6-268.1) | 60.2 (33-78) | 0 (0–1) | 27.3 (9.2–62) | 0.3 (0–1) | 0.9 (0–1) | 0.3 (0–1) | 0.1 (0–1) | 17.8 (14–23) | |
| Attention | No Deficit | 86.1 (11.5-248.5) | 53.7 (25–74) | 0.1 (0–1) | 29.3 (5–65) | 0.6 (0–1) | 0.9 (0–1) | 0.4 (0–1) | 0.1 (0–1) | 18.5 (15–26) |
| p.val | 0.47 | 0.09 | 0.25 | 0.64 | 0.19 | 1.00 | 0.32 | 1.00 | 0.46 |
All p-values are shown as unadjusted. p-value < 0.05 is considered statistically significant.