Table 2.
Outcome variables.
| Intervention Group | Control Group | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Pre-Treatment | Post-Treatment | 2 Months | 3 Months | Pre-Treatment | 1 Week | 2 Months | 3 Months | p Value Time 1 | p Value Group 1 | p Value Group:Time 1 | (95% CI) | |
| MEC-35 | 29.824 ± 2.624 | 31.634 ± 2.395 | 32.071 ± 2.511 | 32.273 ± 2.402 | 29.915 ± 2.639 | 30.085 ± 3.167 | 30.357 ± 3.281 | 30.485 ± 2.78 | <0.001 | <0.001 | 0.002 | 0.008 (0.007, 0.044) |
| Global orientation | 9.198 ± 1.033 | 9.431 ± 0.805 | 9.671 ± 0.714 | 9.545 ± 0.915 | 9.22 ± 0.949 | 9.085 ± 1.323 | 9.024 ± 1.242 | 8.939 ± 1.036 | 0.413 | <0.001 | 0.001 | 0.004 (0.005, 0.037) |
| Time orientation | 4.542 ± 0.715 | 4.681 ± 0.667 | 4.776 ± 0.624 | 4.667 ± 0.771 | 4.497 ± 0.762 | 4.376 ± 0.962 | 4.274 ± 1.034 | 4.212 ± 0.851 | 0.521 | <0.001 | 0.022 | 0 (0.003, 0.033) |
| Spatial orientation | 4.656 ± 0.617 | 4.733 ± 0.565 | 4.894 ± 0.31 | 4.879 ± 0.412 | 4.723 ± 0.581 | 4.709 ± 0.708 | 4.75 ± 0.557 | 4.727 ± 0.57 | 0.061 | 0.81 | 0.611 | 0.006 (0.001, 0.02) |
| Global attention and calculation | 6.099 ± 1.626 | 6.578 ± 1.544 | 6.753 ± 1.55 | 6.606 ± 1.456 | 6.294 ± 1.557 | 6.453 ± 1.694 | 6.357 ± 1.655 | 6.5 ± 1.657 | 0.018 | 0.462 | 0.263 | 0.008 (0, 0.018) |
| Attention | 1.672 ± 1.205 | 2.69 ± 1.398 | 2.765 ± 1.315 | 2.667 ± 1.293 | 1.853 ± 1.394 | 2.65 ± 1.522 | 2.643 ± 1.323 | 2.712 ± 1.465 | <0.001 | 0.805 | 0.76 | 0.008 (0.001, 0.018) |
| Calculation | 4.427 ± 0.985 | 3.888 ± 1.625 | 3.988 ± 1.651 | 3.924 ± 1.582 | 4.475 ± 0.905 | 3.803 ± 1.647 | 3.726 ± 1.689 | 3.788 ± 1.714 | 0.009 | 0.115 | 0.405 | 0.011 (0, 0.013) |
| Short-term memory | 1.718 ± 0.987 | 2.216 ± 0.853 | 2.482 ± 0.796 | 2.606 ± 0.653 | 1.593 ± 1.078 | 1.838 ± 1.066 | 2.036 ± 1.035 | 2.076 ± 1.057 | <0.001 | <0.001 | 0.423 | 0.006 (0.001, 0.022) |
| Language and global praxis | 9.809 ± 0.921 | 10.405 ± 0.78 | 10.165 ± 1.01 | 10.515 ± 0.707 | 9.808 ± 1.101 | 9.718 ± 1.105 | 9.94 ± 1.101 | 9.97 ± 0.96 | <0.001 | <0.001 | <0.001 | 0.008 (0.007, 0.045) |
| Language | 5.344 ± 0.721 | 5.75 ± 0.558 | 5.647 ± 0.685 | 5.833 ± 0.514 | 5.362 ± 0.801 | 5.427 ± 0.78 | 5.576 ± 0.746 | 5.5 ± 0.707 | <0.001 | <0.001 | 0.002 | 0 (0.003, 0.03) |
| Praxis | 4.466 ± 0.683 | 4.664 ± 0.51 | 4.518 ± 0.648 | 4.682 ± 0.501 | 4.452 ± 0.648 | 4.299 ± 0.686 | 4.388 ± 0.638 | 4.47 ± 0.561 | 0.638 | <0.001 | 0.045 | 0.001 (0.003, 0.034) |
MEC-35: Lobo’s cognitive mini-examination. 1 ANOVA test p values for time (within measurement time in each group) and group (between both groups) main effects and group:time interaction; significant if p < 0.05.