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. 2023 Jan 22;15(2):382. doi: 10.3390/pharmaceutics15020382

Table 5.

The kinetic of curcumin release from p(NiPMAm/NiPAm) hydrogels.

Kinetic Model Parameter Sample 10/90/2 Sample 10/90/3
Higuchi
๐น = ๐‘˜๐ปโˆ™๐‘ก1/2
kH 9.218 3.350
R2 โˆ’0.918 โˆ’1.147
AIC 97.98 74.811
Korsmeyerโ€“Peppas
๐น = ๐‘˜๐พ๐‘ƒโˆ™๐‘ก๐‘›
kKP 33.247 12.499
n 0.074 0.063
R2 0.984 0.996
AIC 41.036 โˆ’2.927
Bakerโ€“Lonsdale
3/2[1โˆ’(1โˆ’๐น/100)2/3]โˆ’๐น/100 =๐‘˜ ๐ต๐ฟโˆ™๐‘ก
kBL 0.002 0
R2 โˆ’0.636 โˆ’1.054
AIC 96.078 74.27

kH: the constant of release at Higuchi model; R2: coefficient of determination; AIC: Akaikโ€™s information criterion; F: the fraction of released drug in function of time t; kKP: the constant of release at Korsmeyer-Peppes model that takes into account structural and geometrical characteristics of dosage form; n: the exponent of release/diffusion; kBL: combined constant of release at Baker-Lonsdale model; [60,61,62].