Table 1.

Dolor neuropatique 4; MNSI, Michigan Neuropathy Screening Instrument; mTCNS, modified Toronto Clinical Neuropathy Score; NDS, Neuropathy Disability Score; SFN-SIQ, Small Fiber Neuropathy and Symptoms Inventory; Questionnaire; IpTT, Ipswich touch test; NCM, Nervecheck Master; NCS, Nerve Conduction Studies; CCM, Corneal Confocal Microscopy; IENFD, intraepidermal nerve fibers density; LEPs, laser evoked potentials.

Type of Fibers	Stimulus	Screening Scores	Quantitative Sensory Testing and Neurological Tools	Nerve Conduction Studies/Others	Sensitivity/Specificity
Large (sensory axons) - myelinated α - myelinated β	Tactile Vibration Position	DN4, MNSI, mTCNS, NDS MNSI, mTCNS MNSI, NDS	10 g monofilament, IpTT Neurothesiometer/biothesiometer VibraTip	NCS NCS	DN4 (80/91%) MNSI (40/92%) 10 g monofilament (62.5%) IpTT (50–100/90–98%) Neurothesiometer/biothesio meter (reliability; κ = 0.58–0.65; k = 0.51–0.61) VibraTip (50–62.5/84.2%) NCS (85/95%)
Small (sensory axons) - Aδ-fibers - Unmyelinated C-fibers	Tactile Cold Pressure Warm thermal Pain Sweating	SFN-SIQ SFN-SIQ DN4, mTCNS, SFN-SIQ MNSI, mTCNS, SFN-SIQ	NCM NCM NCM Neuropad, Sudoscan	CCM, IENFD, LEPs CCM, IENFD, LEPs	Neuropad (~90/~70%) Sudoscan (~90%) NCM (AUC 60–85%) CCM (67/71%) IENFD (90/87%) LEPs (91/83%)