Table 1.
Detailed description of the cases.
| LAI Monthly Dose, Timing at First Call |
Patient Age | Alcohol, Drug, Tobacco Use |
Co-Exposures in First Trimester | Delivery Mode, Outcome, and Comments |
APGAR | Hospitalization for Psychosis Relapse |
|---|---|---|---|---|---|---|
| Paliperidone 50 mg, 5 w | 26 | No/no/no | Lorazepam 1 mg | CS a 39 w, female 3020 g | 9/9 | Yes, postpartum |
| Paliperidone 100 mg, 7 w | 32 | No/no/no | CS 40 w, male 3250 g | 9/10 | No | |
| Aripiprazole 400 mg, 6 w | 38 | No/no/no | Interruption of LAI at 23 w CS 31 w 1995 g preterm birth, Down syndrome, fetal hydrops complicated by septic shock, massive anuria and death in 10 days |
6/8 | Yes, postpartum | |
| Aripiprazole 400 mg, 5 w | 25 | No/no/no | VD b female 40 w 3300 g | 9/10 | Yes, postpartum | |
| Paliperidone 100 mg, 6 w | 30 | No/no/no | CS male39 w 3650 g | 10/10 | Yes, postpartum | |
| Paliperidone 100 mg, 7 w | 25 | No/no/no | CS female 40 w 3255 g | 9/10 | No | |
| Aripiprazole 200 mg, 10 w | 31 | No/no/no | Haloperidol 30 mg | Interruption LAI at 14 w AS c 15 w |
----- | No |
| Paliperidone 50 mg, 5 w | 33 | No/no/no | Haloperidol 50 mg | CS, Female 39 w 3100 g | 9/10 | No |
| Aripiprazole 200 mg, 7 w | 35 | No/no/no | Haloperidol 50 mg | AS 9 w | ----- | No |
| Aripiprazole 200 mg, 10 w | 34 | No/no/no | Carbamazepine 600 mg, stopped at 10 w | CS male, 40 w 2900 g | 9/10 | Yes, postpartum |
| Aripiprazole 400 mg, 5 w | 28 | No/no/no | Aripiprazole 15 mg | CS, female 40 w 3140 g | 7/9 | No |
| Aripiprazole 400 mg, 5 w | 43 | No/no/no | VD male 40 w 2300 g | 10/10 | No | |
| Aripiprazole 400 mg, 9 w | 31 | No/no/no | VD male 40 w 3500 g | 8/10 | No | |
| Aripiprazole 400 mg, 8 w | 20 | No/no/no | Haloperidol 50 mg | Stillbirth 26 w | ----- | Yes, after stillbirth |
| Aripiprazole 400 mg, 8 w | 31 | No/no/no | Paroxetine 20 mg | VD female 38 w 3120 g | 9/10 | No |
a CS: cesarian section. b VD: vaginal delivery. c AS: spontaneous abortion (miscarriage). w: week of gestation.