Table 1.
Major members of the subfamily Gammaherpesvirinae a.
| Genus | Virus Species | Abbreviations | Target Cells | Host Target |
Associated Diseases |
|---|---|---|---|---|---|
| Lymphocryptovirus | Epstein-Barr virus, Human gammaherpesvirus 4 |
EBV, HHV-4 |
B cells | Human | Infectious mononucleosis, Nasopharyngeal carcinoma, Hodgkin’s and Burkitt’s lymphomas |
| Rhadinovirus | Kaposi’s sarcoma-associated herpesvirus, Human gammaherpesvirus 8 |
KSHV, HHV-8 | B cells | Human | Kaposi’s sarcoma, Multicentric Castleman ‘s disease, Primary effusion lymphoma |
| Murine gammaherpesvirus 68, Murid gammaherpesvirus 4 | MHV-68, MuHV-4 | B cells/Macrophages | Rodents | B cell lymphomas | |
| Herpesvirus saimiri, Saimiriine gammaherpesvirus 2 | HVS, SaHV-2 |
T cells | Squirrel monkey/non-human primates | T cell lymphomas | |
| Percavirus | Equid gammaherpesvirus 2 | EHV-2 | B cells | Horse | Respiratory symptoms |
| Macavirus a | Alcelaphine gammaherpesvirus 1 | AlHV-1 | T cells | Wildebeest/Other ruminants | Malignant Catarrhal Fever |
| Alcelaphine gammaherpesvirus 2 | AlHV-2 | Unknow | Hartebeest/Barbary red deer/Bison/Topi | Malignant Catarrhal Fever | |
| Alcelaphine gammaherpesvirus 2-like | AlHV-2-like | Unknown | Barbary red deer | Malignant Catarrhal Fever | |
| WD-MCFV-oryx | WD-MCFV-oryx | Unknown | Oryx | No disease | |
| Alcelaphine gammaherpesvirus 2 | AlHV-2 | Unknow | Hartebeest/Barbary red deer/Bison/Topi | Malignant Catarrhal Fever | |
| Ovine gammaherpesvirus 2 | OvHV-2 | T cells | Sheep/Other ruminants | Malignant Catarrhal Fever | |
| Caprine gammaherpesvirus 2 | CpHV-2 | Unknow | Goats/White-tailed deer/Sika deer | Malignant Catarrhal Fever | |
| WD-MCFV–white-tailed deer, Caprine gammaherpesvirus 3 |
CpHV-3 | Unknow | Goat/White-tailed deer/ Red brocket deer /Reindeer |
Malignant Catarrhal Fever | |
| Ibex-WD-MCFV | Ibex-WD-MCFV | Unknown | Ibex/Bongo/Anoa/Pronghorn | Malignant Catarrhal Fever | |
| Muskox-WD-MCFV | Muskox-WD-MCFV | Unknown | Muskox | No diseases | |
| Aoudad-WD-MCFV | Aoudad-WD-MCFV | Unknown | Aoudad | No diseases | |
| Bovine lymphotropic herpesvirus, Bovine gammaherpesvirus 6 | BoHV6 | B cells | Cattle | No disease | |
| Porcine lymphotropic herpesvirus 1, Suid gammaherpesvirus 3 | SuHV3 | Unknown | Swine | Post-transplantation lymphoproliferative disorder (PTLD) | |
| Porcine lymphotropic herpesvirus 2, Suid gammaherpesvirus 4 | SuHV4 | Unknown | Swine | Post-transplantation lymphoproliferative disorder (PTLD) | |
| Porcine lymphotropic herpesvirus 3, Suid gammaherpesvirus 5 | SuHV5 | Unknown | Swine | Post-transplantation lymphoproliferative disorder (PTLD) |
a In the genus Macavirus, AlHV-1, AlHV-2, AlHV-2-like, HiHV-1, and oryx-WD-MCFV infect species of the subfamilies Alcelaphinae/Hippotraginae, while OvHV-2, CpHV-2, CpHV-3, ibex-WD-MCFV, Aoudad-WD-MCF, and Muskox-WD-MCF infect species of the subfamily Caprinae. BoHV-6, SuHV-3, SuHV-4, and SuHV-5 belong to the genus Macavirus but are not associated with WD-MCF.