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. 2023 Feb 14;15(2):535. doi: 10.3390/v15020535

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Reactivity of human plasma samples against A(H1N1)pdm09 viruses. HI (A) and neutralization (B) titers of 63 human serum samples against the indicated seven viruses are plotted as black lines; a small amount of vertical jitter has been added to prevent lines from overlapping each other. The mean of all individuals is shown in red. Antigens are grouped on the x-axis according to the substitutions of interest. Viruses are abbreviated as follows: A/Singapore/GP1908/2015 (Singapore); A/Tokyo/UT-WD039-0/2019 (WD039-0); A/Tokyo/UT-BB251/2019 (BB251); A/Tokyo/UT-BB262/2019 (BB262); A/Tokyo/UT-GR156/2019 (GR156); A/Tokyo/UT-GR253/2020 (GR253); and A/Tokyo/UT-AC109/2020 (AC109). ** indicates p < 0.01 compared with Singapore.