Table 2.
Summary of the main molecular biomarkers and imaging techniques used in the diagnosis of Parkinson’s disease and Alzheimer’s disease.
| DIAGNOSTIC TOOLS IN NEURODEGENERATIVE DISORDERS | ||||
|---|---|---|---|---|
| MOLECULAR BIOMARKERS | IMAGING TECHNIQUES | |||
| Biomarkers in peripheric fluids | Alpha-synuclein in Parkinson’s Disease (PD) | Magnetic Resonance Imaging (MRI) | Structural MRI | |
| Amyloid-β and tau in Alzheimer´s Disease (AD) | ||||
| Functional MRI | ||||
| Inflammation markers | ||||
| Positron Emission Tomography (PET) | PD | DAT imaging | ||
| Exosomes | Neurotransmitters | |||
| Brain-gut denervation | ||||
| Alpha-synuclein | ||||
| Autoantibodies | AD | [18F] FDG–PET | ||
| Amyloid-beta | ||||
| Tau | ||||