Table 3. List of some FDA-approved nanomedicines for anticancer therapeutics.
Name of Nano-formulation | Active Drug Loaded | Nanomaterial Type | Cancer Therapy | Year of Approval | References |
Doxil/Calex | Doxorubicin | Liposome (PEGylated) | HIV-associated Kaposi’s sarcoma, ovarian cancer, metastatic breast cancer, and multiple myeloma | 1995 | [3] |
DaunoXome/Galen | Daunorubicin | Liposome (PEGylated) | HIV-associated Kaposi’s sarcoma | 1996 | [5] |
DepoCyt | Cytosine arabinoside (cytarabine) | Liposome | Neoplastic meningitis | 1999 | [3] |
Eligard | Leuprolide acetate | Polymer | Prostate cancer | 2002 | [10] |
Abraxane | Paclitaxel | Nanoparticle albumin-bound (Nab) | Advanced non-small cell lung cancer, metastatic pancreatic cancer, and metastatic breast cancer | 2005 | [8,9] |
Marqibo | Vincristine | Liposome (non-PEGylated) | Philadelphia chromosome-negative acute lymphoblastic leukemia | 2012 | [5,8] |
Abraxane | Paclitaxel + Gemcitabine | Nab | Metastatic pancreatic cancer | 2013 | [8] |
Onivyde/MM-398/Merrimack | Irinotecan | Liposome (PEGylated) | Metastatic pancreatic cancer (second line) | 2015 | [3,5] |