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. 2023 Jan 26;15(1):e34245. doi: 10.7759/cureus.34245

Table 3. List of some FDA-approved nanomedicines for anticancer therapeutics.

Name of Nano-formulation Active Drug Loaded Nanomaterial Type Cancer Therapy Year of Approval References
Doxil/Calex Doxorubicin Liposome (PEGylated) HIV-associated Kaposi’s sarcoma, ovarian cancer, metastatic breast cancer, and multiple myeloma 1995 [3]
DaunoXome/Galen Daunorubicin Liposome (PEGylated) HIV-associated Kaposi’s sarcoma 1996 [5]
DepoCyt Cytosine arabinoside (cytarabine) Liposome Neoplastic meningitis 1999 [3]
Eligard Leuprolide acetate Polymer Prostate cancer 2002 [10]
Abraxane Paclitaxel Nanoparticle albumin-bound (Nab) Advanced non-small cell lung cancer, metastatic pancreatic cancer, and metastatic breast cancer 2005 [8,9]
Marqibo Vincristine Liposome (non-PEGylated) Philadelphia chromosome-negative acute lymphoblastic leukemia 2012 [5,8]
Abraxane Paclitaxel + Gemcitabine Nab Metastatic pancreatic cancer 2013 [8]
Onivyde/MM-398/Merrimack Irinotecan Liposome (PEGylated) Metastatic pancreatic cancer (second line) 2015 [3,5]