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. 2022 Nov 1;96(3):411–418. doi: 10.1007/s00420-022-01932-x

Table 4.

Relative risk of selected circulatory disease mortality (1950–2016) by cumulative radon exposure among the cohort of Newfoundland fluorspar miners

Cumulative exposure to radon in WLM (quantiles) Deaths Person-years of follow-up Relative Risk*
(95% CI)
Relative Risk
(95% CI)*†
Circulatory disease mortality
 0 105 17,510 1.0 1.0
  > 0– < 4.6 90 24,315 0.99 0.73–1.34 1.05 0.55–1.99
 4.6– < 25.9 95 16,715 1.00 0.75–1.34 1.23 0.66–2.02
 25.9– < 94.7 95 11,400 1.10 0.82–1.47 1.21 0.70–2.14
 94.7+  95 11,710 1.03 0.76–1.40 1.06 0.61–1.85
Ischemic heart disease
 0 55 17,510 1.0 1.0
  > 0– < 4.6 55 24,315 0.98 0.66–1.45 1.24 0.55–2.80
 4.6– < 25.9 60 16,715 1.06 0.73–1.56 1.31 0.63–2.72
 25.9– < 94.7 60 11,400 1.19 0.82–1.74 1.31 0.62–2.77
 94.7+  55 11,710 0.99 0.66–1.48 1.14 0.55–2.37
Acute myocardial infarction
 0 30 17,510 1.0 1.0
  > 0– < 4.6 30 24,315 1.08 0.64–1.82 1.30 0.42–3.98
 4.6– < 25.9 30 16,715 1.01 0.60–1.70 1.26 0.47–3.41
 25.9– < 94.7 40 11,400 1.36 0.83–2.23 1.13 0.41–3.12
 94.7+  40 11,710 1.39 0.84–2.30 1.56 0.60–4.06
Cerebrovascular disease
 0 10 17,510 1.0
  > 0– < 4.6 10 24,315 0.81 0.33–2.01 RRs suppressed
 4.6– < 25.9 15 16,715 1.56 0.72–3.40 Due to small
 25.9– < 94.7 15 11,400 1.26 0.56–2.85 Counts
 94.7+  10 11,710 0.69 0.26–1.86

*Relative risks were adjusted by attained age, calendar period, and average number of cigarettes smoked daily

Miners with missing smoking data were excluded