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. 2023 Feb 17;24(2):275–286. doi: 10.1007/s40257-022-00753-5

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© The Author(s) 2023

Open AccessThis article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc/4.0/.

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Fig. 4 — Immunohistochemical detection of MMP-1, MMP-2, and MMP-13 in lesions of stasis dermatitis. Increased immunoreactive staining was observed in skin from stasis dermatitis lesions for a MMP-1, b MMP-2, and c MMP-13. Representative photographs from one patient are shown. The experiment was repeated with comparable results (n = 2 for stasis dermatitis; n = 2 for control). Figure used with permission from Herouy et al. [46] J Dermatol Sciences, 2001. MMP matrix metalloproteinase