Table 2.

Summary of the treatments used for stasis dermatitis

	Edema	Feeling of heaviness in legs	Hyperpigmentation	Inflammation	Leg cramps	Pain	Prevent ulcer recurrence	Promote healing of ulcers	Pruritus	Xerosis
Nonpharmacological: exercise, walking, leg elevation, stockings, bandages, topical dressings (Unna boot)	X		X	X		X
Non-soap cleansers, barrier preparations, bland emollients			X
Moisturizers										X
Topical high- and mid-potency corticosteroids									X
Topical calcineurin inhibitors (topical tacrolimus [off-label])									X
Antihistamines									X
Pulsed light treatments			X
Oral pentoxifylline						X		X	X
Topical pentoxifylline and phlebotonics						X		X
Venoactive medications (escin, micronized purified flavonoid fraction), calcium channel blocker (amlodipine), angiotensin-converting enzyme inhibitors, angiotensin receptor blockers	X
Hydroxyethylrutosides		X			X	X
Ultrasound-guided foam sclerotherapy, endovenous thermal ablation, ambulatory phlebectomy							X	X
Topical phosphodiesterase 4 inhibitors (crisaborole [off-label])				X					X
Oral analgesics (anti-inflammatory medications, acetaminophen, metamizole)				X		X
Topical anesthetic creams (prilocaine and lidocaine)						X
Antibiotics and antiseptics								X