Table 2.

Characteristics and markers of metabolic health of 218 DONALD participants.

	N	Overall, N = 2181	Male, N = 881	Female, N = 1301	p-value2
BMI [kg/m2] at blood draw	218	22.30 [20.65, 24.91]	23.25 [21.21, 26.16]	21.89 [20.31, 24.09]	0.005
BMI [kg/m2] at urine collection	218	21.88 [19.96, 23.63]	22.06 [20.38, 23.54]	21.85 [19.88, 23.68]	0.4
Age [years] at blood draw	218	18.00 [18.00, 23.00]	18.00 [18.00, 23.00]	18.00 [18.00, 23.75]	0.5
Age [years] at urine collection	218	18.00 [17.00, 18.00]	18.00 [16.00, 18.00]	18.00 [17.00, 18.00]	0.7
Age difference [years] between last dietary record and blood draw	218	1.00 [0.00, 6.75]	1.00 [0.00, 4.00]	1.50 [0.00, 7.00]	0.7
Age difference [years] between last dietary record and urine collection	218	0.00 [0.00, 0.00]	0.00 [0.00, 0.00]	0.00 [0.00, 0.00]	0.4
3-Methylcrotonylglycine	206	0.99 [0.71, 1.25]	1.00 [0.83, 1.25]	0.94 [0.61, 1.24]	0.075
5-Dodecenoylcarnitine (c12:1)	218	0.93 [0.58, 1.38]	1.18 [0.73, 1.66]	0.84 [0.50, 1.26]	0.001
7-Hydroxyindole sulfate	211	0.92 [0.54, 1.62]	1.25 [0.81, 1.97]	0.68 [0.46, 1.11]	< 0.001
Citraconate/glutaconate	218	1.00 [0.63, 1.80]	1.09 [0.72, 2.00]	0.88 [0.57, 1.68]	0.042
Decanoylcarnitine (c10)	217	0.95 [0.64, 1.44]	0.92 [0.64, 1.58]	1.00 [0.64, 1.39]	0.7
Formiminoglutamate	218	0.97 [0.64, 1.33]	1.01 [0.76, 1.35]	0.85 [0.54, 1.31]	0.020
Glucuronide of c10h18o2 (12)	217	1.00 [0.68, 1.58]	1.03 [0.79, 1.44]	0.98 [0.66, 1.65]	0.4
Glutamine conjugate of c8h12o2 (1)	218	0.98 [0.68, 1.54]	0.98 [0.72, 1.45]	0.99 [0.63, 1.58]	0.7
Glycine conjugate of c10h14o2 (1)	218	0.95 [0.59, 1.68]	1.00 [0.68, 1.92]	0.87 [0.59, 1.63]	0.4
Guanidinosuccinate	218	0.96 [0.70, 1.30]	1.10 [0.81, 1.31]	0.83 [0.61, 1.23]	0.005
Hippurate	218	0.99 [0.69, 1.44]	0.92 [0.69, 1.35]	1.07 [0.70, 1.50]	0.3
Indole-3-acetamide	198	0.93 [0.58, 1.87]	1.06 [0.57, 2.03]	0.88 [0.61, 1.78]	0.5
Isobutyrylglycine (c4)	218	0.98 [0.67, 1.31]	1.08 [0.82, 1.33]	0.87 [0.61, 1.28]	0.011
Isovalerylglutamine	218	0.99 [0.66, 1.36]	1.15 [0.96, 1.44]	0.83 [0.56, 1.16]	< 0.001
Isovalerylglycine	218	1.00 [0.69, 1.44]	1.21 [0.82, 1.51]	0.86 [0.62, 1.34]	< 0.001
N6-methyladenosine	215	0.99 [0.71, 1.42]	1.06 [0.77, 1.44]	0.96 [0.69, 1.41]	0.14
Nicotinamide n-oxide	214	1.01 [0.60, 1.59]	1.00 [0.65, 1.50]	1.05 [0.57, 1.78]	0.7
Proline	218	0.99 [0.69, 1.27]	1.09 [0.78, 1.42]	0.90 [0.66, 1.13]	0.004
Succinimide	217	0.98 [0.70, 1.35]	1.14 [0.90, 1.60]	0.86 [0.60, 1.22]	< 0.001
Thymine	217	1.00 [0.75, 1.33]	1.09 [0.82, 1.42]	0.90 [0.64, 1.23]	0.004
Tigloylglycine	218	0.93 [0.71, 1.28]	1.11 [0.83, 1.41]	0.82 [0.68, 1.23]	0.004
Vanillylmandelate (vma)	218	0.99 [0.79, 1.36]	1.11 [0.86, 1.44]	0.93 [0.76, 1.27]	0.007

¹Median [IQR].

²Wilcoxon rank sum test Males VS Females.

Unknown metabolites are not displayed.