Table 2.
Brain regions showing functional differences between DFP and HC identified by voxel-wise meta-analysis.
Regions | Cluster size (voxels) | Peak MNI coordinate | SDM-z | P value |
---|---|---|---|---|
DFP > HC | ||||
Left cerebellar hemisphere | 187 | −18, −58, −20 | 3.20 | 6.93 × 10−4 |
Left putamen | 158 | −20, 10, −4 | 4.24 | 1.11 × 10−5 |
Right calcarine sulcus | 184 | 14, −94, 2 | 3.43 | 3.02 × 10−4 |
Right caudate | 24 | 8, 8, 6 | 3.17 | 7.63 × 10−4 |
Right caudate | 46 | 16, 14, 16 | 3.23 | 6.11 × 10−4 |
DFP < HC | ||||
Bilateral posterior cingulate gyrus | 280 | 4, −58, 14 | −4.13 | 1.81 × 10−5 |
Bilateral precuneus | 227 | 2, −46, 36 | −3.97 | 3.56 × 10−5 |
Right cuneus | 94 | 10, −76, 40 | −3.48 | 2.47 × 10−4 |
Right precentral gyrus | 187 | 54, −10, 38 | −3.75 | 8.82 × 10−5 |
Right inferior parietal lobule | 101 | 50, −52, 44 | −3.68 | 1.18 × 10−4 |
DFP patients with drug-naive first-episode psychosis, HC healthy controls, MNI Montreal Neurological Institute, SDM seed-based d mapping.