Table 2.
Concordance between GeneScan PCR and ASO-PCR analyses for MRD detection
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|---|---|---|---|---|---|
| Samples | ASO-qPCR and GSA (n) | GSA+/ASO+ | GSA-/ ASO- | GSA-/ ASO+ | Concordance (%) |
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| Total samples | 256 | 135 | 87 | 34 | 86.7 |
| Diagnosis | 35 | 35 | 0 | 0 | 100.0 |
| During induction, day 14 | 35 | 30 | 5 | 0 | 100.0 |
| End of induction, day 28 | 35 | 27 | 8 | 0 | 100.0 |
| Consolidation treatment, day 58 | 33 | 18 | 11 | 4 | 87.9 |
| Day 88 | 30 | 12 | 13 | 5 | 83.3 |
| Other time-points | 88 | 13 | 50 | 25 | 71.6 |
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ASO-PCR; Allele-specific oligonucleotide-quantitative polymerase chain reaction, MRD; Minimal residual disease, and GSA; GeneScanning analysis.