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. Author manuscript; available in PMC: 2023 Feb 26.
Published in final edited form as: J Invest Dermatol. 2021 Aug 27;142(3 Pt A):583–593.e5. doi: 10.1016/j.jid.2021.08.397

Figure 5. Ovol1 loss alters neutrophil dynamics, and neutrophil depletion rescues psoriasis-like phenotypes in Ovol1−/− skin.

Figure 5.

(a, b) Shown are representative images of immunostaining in (a) Ovol1 SSKO and (b) Ovol1−/− mice. (a, b, d) Arrows point to neutrophils. (c) Design of neutrophil depletion experiments in d–f. IgG was used as a control. (d) Immunostaining on d3. (a, b) Bar = 50 μm and (d) Bar = 100 μm. (e) External appearance and (f) phenotypic score (n = 3) at the respective times. *P < 0.05. Error bars represent mean ± SEM. Ab, antibody; d, day; h, hour; IMQ, imiquimod; K, keratin; SSKO, skin epithelia–specific knockout.