Table 6.

A Summary of ANOVA Results for the Quadratic Models for the Dependent Variables

	Particle Size (nm)		Polydispersity Index		Zeta Potential (mV)
	Coefficient	p value	Coefficient	p value	Coefficient	p value
Model		≤ 0.0001		≤0.0001		≤0.0001
Intercept	88.10		0.2421		−35.26
X1	18.25	≤ 0.0001	−0.0020	0.6927	−2.25	0.0001
X2	−18.34	≤ 0.0001	−0.0505	≤0.0001	4.07	≤ 0.0001
X3	−2.85	0.0184	−0.0395	≤0.0001	0.9669	0.0263
X1X2	−1.84	0.1958	−0.0033	0.6187	−0.0375	0.9399
X1X3	−2.61	0.0770	−0.0098	0.1544	−0.0125	0.9799
X2X3	0.8375	0.5417	0.0365	0.0002	0.8625	0.1058
X12	0.5477	0.5914	−0.0009	0.8518	1.37	0.0035
X22	7.14	≤ 0.0001	0.0246	0.0004	0.0449	0.9037
X32	0.0174	0.9863	0.0339	≤ 0.0001	−0.5562	0.1549
Residual
Lack of Fit		0.3907		0.1473		0.3805
Fit statistics
R2	0.9863		0.9661		0.9486
R2 (adjusted)	0.9739		0.9357		0.9024
R2 (predicted)	0.9283		0.7964		0.7380
Adequate precision	30.7711		16.6424		16.2467

Note: Statistically significant values at p < 0.05 are underlined.

Abbreviations: X₁, binary mixture concentration (% w/v); X₂, Total surfactant concentration (% w/v); X₃, Sonication time.