Table 4:
Univariable GEE analysis of baseline variables and PROMIS sleep disturbance across 4 time points (baseline, 2 weeks, 6 months, and 12 months)
| Baseline Variable | B (CI) | SE | Test Statistic | p |
|---|---|---|---|---|
| Univariable GEE | ||||
| Sociodemographics | ||||
| Age | −0.15 (−0.21, −0.09) | 0.03 | 22.26 | <.001 |
| Education | −0.78 (−1.45, −.011) | 0.34 | 5.21 | .022 |
| Non-Caucasian | −0.61 (−3.31, 2.10) | 1.38 | 0.19 | .661 |
| Surgical Variables | ||||
| Surgery/reconstruction type | ||||
| Breast conserving surgery (Lumpectomy) | Ref | Ref | Ref | Ref |
| Mastectomy | −0.95 (−3.40, 1.49) | 1.25 | 0.59 | .444 |
| Mastectomy with reconstruction | 1.70 (−0.06, 3.45) | 0.90 | 3.59 | .058 |
| Axillary procedure | 3.65 (1.42, 5.88) | 1.14 | 10.30 | .001 |
| Treatment variables | ||||
| Radiation therapy | −0.62 (−2.22, 0.99) | 0.82 | 0.57 | .451 |
| Chemotherapy* | 1.70 (0.03, 3.33) | 0.84 | 3.98 | .046 |
| Breast Cancer Pain questionnaire (BCPQ) | ||||
| Pain Severity Index (PSI) | 0.22 (0.10, 0.35) | 0.06 | 11.87 | .001 |
| Opioid use | 4.97 ( 2.19, 7.74) | 1.42 | 12.31 | <.001 |
| Psychological Variables | ||||
| Pain Catastrophizing | 0.25 (0.13, 0.37) | 0.06 | 15.66 | <.001 |
| Anxiety (PROMIS-SF) | 0.49 (0.34, 0.65) | 0.08 | 40.20 | <.001 |
| Depression (PROMIS-SF) | 0.45 (0.26, 0.65) | 0.10 | 21.46 | <.001 |
| Negative Affect (PANAS) | 0.35 (0.19, 0.50) | 0.08 | 18.23 | <.001 |
| Positive Affect (PANAS) | −0.26 (−0.38, −0.15) | 0.06 | 20.41 | <.001 |
| Somatization (BSI) | 0.89 (00.50, 1.27) | 0.20 | 20.65 | <.001 |