Table 1.
Test–retest analysis of features used to describe inflammatory and chronic changes on MRI in 60 children through young adults (35 females) ages 6–20 years with juvenile idiopathic arthritis and hip involvement
| Type of damage | Right hip | Left hip | ||
|---|---|---|---|---|
| Intra-reader kappa (95% CI) | Inter-reader kappa (95% CI) |
Intra-reader kappa (95% CI) |
Inter-reader kappa (95% CI) |
|
| Inflammatory domain | ||||
| Synovial enhancement (0–3) | 0.7 (0.6–0.9) | 0.3 (0.2–0.4) | 0.7 (0.5–0.8) | 0.4 (0.2–0.5) |
| Synovial enhancement (0–2) | 0.8 (0.6–0.9) | 0.4 (0.2–0.6) | 0.7 (0.5–0.8) | 0.5 (0.3–0.7) |
| Synovial enhancement (0–1) | 0.7 (0.4–1.0) | 0.2 (–0.1–0.5) | 0.5 (0.0–0.9) | 0.1 (–0.2–0.5) |
| Synovial thickening subjective (0–3) | 0.9 (0.8–1.0) | 0.5 (0.3– 0.7) | 0.8 (0.6– 0.9) | 0.4 (0.2–0.6) |
| Effusion (0–4) | 0.6 (0.4–0.8) | 0.4 (0.2–0.6) | 0.7 (0.5–0.8) | 0.3 (0.2–0.4) |
| Overall synovial inflammation (0–3) | 0.8 (0.6–1.0) | 0.4 (0.2–0.6) | 0.7 (0.5–0.9) | 0.4 (0.3–0.6) |
| Overall degree of inflammation, including effusion (0–3) | 0.7 (0.5–0.9) | 0.6 (0.4–0.7) | 0.7 (0.5–0.9) | 0.6 (0.4–0.7) |
| Bone marrow edema | ||||
| Femoral epiphysis (0–2) | 0.7 (0.5–0.9) | 0.4 (0.1–0.6) | 0.7 (0.5–0.9) | 0.3 (0.1–0.6) |
| Acetabulum (0–1) | 0.7 (0.6–0.9) | 0.2 (0.0–0.4) | 0.7 (0.5–0.9) | 0.3 (0.1–0.4) |
| Femoral neck (0–1) | 0.7 (0.5–0.9) | 0.3 (0.0–0.5) | 0.7 (0.6–0.9) | 0.3 (0.0–0.5) |
| Structural bone damage domain | ||||
| Erosion | ||||
| Femoral head (0–3) | 0.7 (0.5–0.9) | 0.4 (0.2–0.6) | 0.8 (0.6–0.9) | 0.5 (0.3–0.7) |
| Femoral neck (0–1) | 0.8 (0.5–1.0) | 0.2 (0.1–0.6) | 0.7 (0.5–0.9) | 0.1 (0.1–0.4) |
| Acetabulum (0–3) | 0.6 (0.4–0.8) | 0.6 (0.4–0.8) | 0.7 (0.5–0.8) | 0.6 (0.4–0.8) |
| Acetabulum (0–2) | 0.6 (0.4–1.0) | 0.3 (0.1–0.5) | 0.7 (0.5–0.8) | 0.4 (0.2–0.6) |
| Active erosion femoral head (0–1) | 0.9 (0.8–1.0) | 0.6 (0.3–0.9) | 0.9 (0.7–1.0) | 0.6 (0.4–0.9) |
| Flattening of the femoral heada (0–4) | 0.7 (0.5–0.9) | 0.4 (0.2–0.6) | 0.6 (0.4–0.8) | 0.3 (0.1–0.5) |
| Flattening femoral head Moseb (0–4) | 0.7 (0.5–0.9) | 0.3 (0.1–0.5) | 0.6 (0.4–0.8) | 0.3 (0.1–0.5) |
| Bone cyst (0–1) | ||||
| Femoral head | 0.9 (0.6–1.0) | 0.7 (0.4–1.0) | 0.8 (0.6–1.0) | 0.7 (0.5–1.0) |
| Acetabulum | 0.8 (0.5–1.0) | 0.3 (0.0–0.7) | 0.8 (0.5–1.0) | 0.6 (0.3–0.9) |
| Enlarged fovea (0–2) | 0.7 (0.6–0.9) | –0.1 (0.2–0.1) | 0.8 (0.6–0.9) | 0.1 (0.1–0.2) |
| Sclerosis (0–1) | 0.8 (0.6–0.9) | 0.1 (0.1–0.2) | 0.8 (0.7–1.0) | 0.1 (0.0–0.2) |
| Osteophytes (0–1) | 0.9 (0.8–1.0) | 0.0 (0.0–0.2) | 0.9 (0.8–1.0) | 0.2 (0.0–0.4) |
| Joint space width (0–3) | 0.7 (0.6–0.9) | 0.2 (0.0–0.4) | 0.6 (0.5–0.8) | 0.2 (0.1–0.4) |
| Cartilage changes (0–4) | 0.4 (0.3–0.6) | 0.3 (0.1–0.4) | 0.4 (0.2–0.6) | 0.3 (0.1–0.4) |
CI confidence interval
aFlattening of femoral head as assessed subjectively
bFlattening of femoral head as assessed using a Mose circle