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Effect of persistent IL-1β exposure on the marker gene expression of human OA chondrocytes. Human OA chondrocytes were incubated for 6 days with 0.1 ng/ml or without IL-1β (n = 8 per group from 8 different donors). Data is representative of the mean fold change compared to control (without IL-1β) +/- SEM of (A) COL1A2, (B) COL2A1, (C) SOX9, (D) ACAN, (E) IL-6, and (F) IL-8. For fold change vs. control, each control was set to 1. (G) quantity of living cells. *p<0.05.
