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. 2023 Feb 13;14:1116839. doi: 10.3389/fimmu.2023.1116839

Figure 10.

Figure 10

Expression analysis and experimental validation of PGK1. (A) Pan-cancer expression profile of PGK1. (B–D) The overall survival (OS), disease-specific survival (DSS), and progression-free survival (PFS) analysis of PGK1 in the TCGA cohort. (E) The Relapse free survival (RFS) analysis of PGK1 in the GSE22219 cohort. (F) PCR assay of clinical samples. PGK1 was highly expressed in BC. (G) PCR assay revealed the expression of PGK1 in different cell lines. PGK1 was highly expressed in four BC cell lines compared to HBL-100 cell lines. (H) PGK1 was knocked down in MCF-7 and MDA-MB-231. (I, J) CCK-8 showed that the proliferation activity of the cells that knockdown PGK1 was dramatically reduced. *P<0.05, **P< 0.01, ***P<0.001.