Figure 11.
In vitro experiment after PGK1 knockdown. (A) After PGK1 knockdown, the cloning ability of MDA-MB-231 and MCF-7 cell lines decreased significantly. (B) Healing test. After PGK1 knockdown, the migration ability of MDA-MB-231 and MCF-7 cell lines decreased significantly. (C) Transwell assay. After PGK1 knockdown, the migration and invasion abilities of MDA-MB-231 and MCF-7 cell lines were significantly decreased. (D) Photographs of tumors obtained from the different groups of nude mice transfected with sh-NC, sh-PGK1. The average weight and tumor size were used to observe tumors. (*P<0.05, **P<0.01, ***P<0.001).
