Table 2.
Two-sample multivariable Mendelian randomization analysis of the relationship for hyperthyroidism or hypothyroidism on SLE.
| Exposure | Outcome | Method | nSNP | OR | 95%CI | P-value |
|---|---|---|---|---|---|---|
| Hyperthyroidism | SLE | MRE-IVW | 2 | 1.395 | (0.984, 1.978) | 0.061 |
| Hypothyroidism | SLE | MRE-IVW | 35 | 1.290 | (0.823, 2.022) | 0.266 |
SLE, systemic lupus erythematosus; SNP, single-nucleotide polymorphism; MRE-IVW, multiplicative random effects-inverse variance weighted.