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. 2023 Feb 13;14:1125415. doi: 10.3389/fimmu.2023.1125415

Table 2.

Two-sample multivariable Mendelian randomization analysis of the relationship for hyperthyroidism or hypothyroidism on SLE.

Exposure Outcome Method nSNP OR 95%CI P-value
Hyperthyroidism SLE MRE-IVW 2 1.395 (0.984, 1.978) 0.061
Hypothyroidism SLE MRE-IVW 35 1.290 (0.823, 2.022) 0.266

SLE, systemic lupus erythematosus; SNP, single-nucleotide polymorphism; MRE-IVW, multiplicative random effects-inverse variance weighted.