Table 1.
Correlations between predicted AD values and true values under different models and different selected miRNA panels.
| miRNA | Whole genome miRNA expression (1,605) | Spearman correlation (top 400) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Scores | Accuracy | Precision | Recall | F1_score | AUPR | AUC | Accuracy | Precision | Recall | F1_score | AUPR | AUC |
| SVC | 0.8342 | 0.8926 | 0.8952 | 0.8939 | 0.9087 | 0.8126 | 0.7785 | 0.8741 | 0.8364 | 0.8549 | 0.8837 | 0.7339 |
| SVR (linear) | 0.7217 | 0.8526 | 0.7668 | 0.8074 | 0.9054 | 0.7855 | 0.8171 | 0.842 | 0.9213 | 0.8799 | 0.9217 | 0.8253 |
| SVR (rbf) | 0.8851 | 0.879 | 0.9854 | 0.9292 | 0.9274 | 0.8514 | 0.8926 | 0.8862 | 0.9863 | 0.9335 | 0.9273 | 0.8564 |
| KNN (regression) | 0.8235 | 0.8297 | 0.9736 | 0.8959 | 0.9015 | 0.7703 | 0.8296 | 0.8342 | 0.9755 | 0.8993 | 0.9195 | 0.806632 |
| miRNA | 3D and expression overlap (214) | 3D cluster, DBSCAN (100) | ||||||||||
| Scores | Accuracy | Precision | Recall | F1_score | AUPR | AUC | Accuracy | Precision | Recall | F1_score | AUPR | AUC |
| SVC | 0.8266 | 0.8825 | 0.8972 | 0.8898 | 0.9173 | 0.817 | 0.8449 | 0.8685 | 0.9442 | 0.9047 | 0.92 | 0.8186 |
| SVR (linear) | 0.8169 | 0.8169 | 0.9637 | 0.8843 | 0.9197 | 0.8215 | 0.7513 | 0.7465 | 0.9943 | 0.8528 | 0.9132 | 0.79 |
| SVR (rbf) | 0.8853 | 0.8797 | 0.9833 | 0.9286 | 0.9272 | 0.8571 | 0.8686 | 0.8692 | 0.9734 | 0.9183 | 0.9286 | 0.8553 |
| KNN (regression) | 0.8411 | 0.8362 | 0.9902 | 0.9067 | 0.9172 | 0.8002 | 0.8426 | 0.8376 | 0.9902 | 0.9075 | 0.9153 | 0.8052 |