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. Author manuscript; available in PMC: 2023 Feb 27.
Published in final edited form as: J Steroid Biochem Mol Biol. 2020 Jan 25;199:105599. doi: 10.1016/j.jsbmb.2020.105599

Table 2.

H-score summary of PR and PRB positivity in human tissues in each sex and range of age fetal cases (19 to 41 weeks prenatal), pediatric cases (0 to 10 years old), young cases (21 to 42 years old), and old cases (54 to 79 years old)

Range of age Fetal Pediatric
Sex Male Female Male Female
Antibody PR PRB PR PRB PR PRB PR PRB
Pituitary (endocrine cells in anterior lobe) None None None None 1 1 1 1
lung (bronchus submucosal gland) Neg Neg Neg Neg Neg Neg Neg Neg
Esophagus Neg Neg Neg Neg Neg Neg Neg Neg
Stomach (fundic gland epithelial cells) 5 5 25 20 20 10 60 60
Small intestine (epithilial cell in crypt) Neg Neg Neg Neg Neg Neg Neg Neg
Colon (epithilial cell in crypt) Neg Neg Neg Neg 30 20 10 10
Pancreas (islet of Langerhans) Neg Neg Neg Neg 30 1 1 1
    (acinar cells) Neg Neg Neg Neg 10 5 35 20
Liver (central and portal vein) Neg Neg 5 2 Neg Neg Neg Neg
Kidney (proximal and distal tubules) 35 35 30 5 5 1 15 5
Urinary bladder (epithelial cells) Neg Neg Neg Neg 5 5 40 10
Adrenal gland (zona glomerulosa) None None None None 1 1 30 10
      (zona fasciculata) None None None None 90 30 90 80
      (zona reticularis) None None None None 90 40 90 80
      (medulla) None None None None 5 1 10 5
Skin (keratinocye in epidermis) None None None None 5 1 5 1
Testis (leydig cells) 50 10 None None Neg Neg None None
   (epithelial cell of epididymis) Neg Neg None None Neg Neg None None
Prostate Neg Neg Neg Neg Neg Neg Neg Neg
Uterus (endometrial epithelial cells) None None 30 Neg None None 50 50
   (endomtrial stromal cells) None None 10 <1 None None 60 <1
Ovary (epithelial cells) None None 10 1 None None 20 5
   (glanular cells) None None 40 40 None None None None
Range of age Young Old
Sex Male Female Male Female
Antibody PR PRB PR PRB PR PRB PR PRB
Pituitary (endocrine cells in anterior lobe) 10 5 5 1 15 1 10 5
lung (bronchus submucosal gland) Neg Neg 30 10 50 30 20 20
Esophagus Neg Neg Neg Neg Neg Neg Neg Neg
Stomach (fundic gland epithelial cells) 10 5 10 1 20 5 70 50
Small intestine (epithilial cell in crypt) 10 5 Neg Neg Neg Neg Neg Neg
Colon (epithilial cell in crypt) Neg Neg 5 1 30 20 20 10
Pancreas (islet of langerhans) 30 1 50 1 20 10 40 1
    (acinar cells) 1 1 5 5 5 5 10 5
Liver (central and portal vein) 30 5 50 10 10 5 20 20
Kidney (proximal and distal tubules) 70 40 70 50 80 30 40 20
Urinary bladder (epithelial cells) 5 1 Neg Neg Neg Neg Neg Neg
Adrenal gland (zona glomerulosa) 50 50 80 80 10 5 80 80
      (zona fasciculata) 90 70 90 90 60 40 90 90
      (zona reticularis) 90 70 90 90 60 50 90 90
      (medulla) 1 1 1 1 1 1 1 1
Skin (keratinocye in epidermis) 1 Neg Neg Neg 1 1 10 10
Testis (leydig cells) 40 30 None None 50 40 None None
   (epithelial cell of epididymis) 1 1 None None 70 5 None None
Prostate Neg Neg Neg Neg Neg Neg Neg Neg
Uterus (endometrial epithelial cells) None None 90 1 None None 1 1
   (endometrial stroma cells) None None 40 <1 None None 30 <1
Ovary (epithelial cells) None None 50 20 None None 40 1
   (glanular cells) None None None None None None None None
   (lutenizing cells) None None 5 <1 None None None None
   (Fallopian tube epithelium) None None 80 20 None None 30 20
Placenta (cytotophoblast) None None 5 <1 None None None None
Breast (ductal cells) None None 50 1 None None 70 30

Mark: None = no cases, Neg = negative for PR or PRB