Table 4.

Prosthesis-related mechanical complications of patients in the included studies.

Study	Mechanical complications	Hypothyroid group, n (%)	Control group, n (%)	OR	95% CI	P-value
Jing et al. (14)	Peri-prosthetic fracture	1 (0.3)	0 (0)	1.00	0.95–1.05	0.317
Buller et al. (7)
	Aseptic loosening	69 (0.07)	60 (0.06)	1.119	0.787–1.590	0.531
	Dislocation	453 (0.46)	355 (0.36)	1.258	1.095–1.446	0.01
	Broken implant	20 (0.02)	20 (0.02)	1.05	0.569–1.937	0.876
	Peri-prosthetic fracture	177 (0.18)	148 (0.15)	1.153	0.927–1.434	0.202
	Other	60 (0.06)	39 (0.04)	1.6	1.078–2.376	0.019
Yuan et al. (16)	Aseptic loosening	0 (0)	0 (0)	N/A	N/A	1
Yuan et al. (17)	Aseptic loosening	0 (0)	0 (0)	N/A	N/A	1