Table 1.
Patient characteristics.
| Patient characteristics | Reference | iTTPa | Septic DICa | P value |
|---|---|---|---|---|
| Numberb | - | 35 | 30 | - |
| Age | - | 55.0 (42.0 to 68.5) | 70.5 (64.5 to 77.0) | <.01 |
| Sex (M/F) | - | 15/20 | 16/14 | .11 |
| ADAMTS-13 activity (%) | 50 to 150 | <0.5 (<0.5 to <0.5) | 31.8 (20.0 to 38.9) | <.01 |
| ADAMTS-13 inhibitor (BU/mL) | <0.5 | 3.0 (1.8 to 4.2) | <0.5 (<0.5 to <0.5) | <.01 |
| Hemoglobin (g/dL) | M:13.7 to 16.8 | 8.4 (7.1 to 9.4) | 10.5 (9.5 to 12.6) | <.01 |
| F:11.6 to 14.8 | ||||
| White blood cell (×103/μL) | 3.3 to 8.6 | 7.1 (4.7 to 10.0) | 9.5 (5.1 to 12.9) | .31 |
| Platelet (×109/L) | 158 to 348 | 12.0 (7.3 to 17.8) | 39.0 (18.5 to 48.8) | <.01 |
| LDH (U/L) | 120 to 220 | 888 (641 to 1438) | 462 (309 to 777) | <.01 |
| Creatinine (mg/dL) | M:0.65 to 1.05 | 0.77 (0.88 to 1.17) | 2.13 (1.27 to 3.50) | <.01 |
| F:0.45 to 0.80 | ||||
| T-Bil (mg/dL) | 0.2 to 1.1 | 2.7 (2.2 to 4.5) | 1.9 (0.8 to 4.7) | .13 |
ADAMTS-13, a disintegrin-like metalloproteinase with thrombospondin type 1 motifs 13; BU, Bethesda unit; DIC, disseminated intravascular coagulation; iTTP, immune-mediated thrombotic thrombocytopenic purpura; LDH, lactate dehydrogenase; T-Bil, total bilirubin.
a
Each data are described as median (first quartile to third quartile).
b
All patients were Japanese.